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Dr. Julie Pollock
Assistant Professor of Chemistry
Profile
My lab utilizes chemical biology techniques, biochemical methods, and organic synthesis to understand breast cancer and lung cancer development and progression. In particular, we are interested in nuclear receptor function, phosphorylation signaling pathways, and the link between cancer and inflammation.
Grants and Fellowships

201: Mary Louise Andrews Award for Cancer Research, Virginia Academy of Sciences

2013-2014: NIH Postdoctoral Fellowship in Endocrine, Developmental, and Reproductive Toxicology

2011: ACS Biological Division Travel Grant

Presentations

Strategies towards ligand-selective modulation of nuclear receptors. Institute for Structural Biology, Drug Discovery and Development. Virginia Commonwealth University, Richmond, VA, May 2016.

Pollock, J. A.; Saijo, K.; Glass, C. K.; Katzenellenbogen, J. A. Characterization of Estrogen Receptor Ligands in Microglia-Mediated Inflammation. Interdisciplinary Environmental Toxicology Seminar Series, University of Illinois, Urbana, IL, February 2014.

Pollock, J. A.; McCafferty, D.G. LSD1: Inhibition and Implications in Breast Cancer. Duke University Breast Cancer Forum, Durham, NC, September 2011.

Selected Publications
Articles
Pollock, J.A.; Wardell, S.E.; Parent, A.A.; Stagg, D.B.; Ellison, S.J.; Alley, H.M.; Chao, C.A.; Lawrence, S.A.; Stice, J.P.; Spasojevic, I.; Baker, J.G.; Kim, S.H.; McDonnell, D.P.; Katzenellenbogen, J.A.; Norris, J.D. “Inhibiting androgen receptor nuclear entry in castration-resistant prostate cancer.” Nature: Chem. Biol. 2016, 12, 795-801.
Pollock, J.A.; Kim, S.H.; Katzenellenbogen, J.A. “Imidoyl dichlorides as new reagents for the rapid formation of 2-aminobenzimidazoles and related azoles.” Tetrahedron Lett. 2015, 26, 6097-6099.

Nwachukwu, J. C.; Srinivasan, S.; Bruno, N. E.; Parent, A. A.; Hughes, T. S.; Pollock, J. A.; Gjyshi, O.; Cavett, V.; Nowak, J.; Garcia-Ordonez, R. D.; Houtman, R.; Griffin, P. R.; Kojetin, D. J.; Katzenellenbogen, J. A.; Conkright, M. D.; Nettles,  K. W. “Resveratrol modulates the inflammatory response via an estrogen receptor-signal integration network.” eLife 2014, 3, e02057.

Pollock, J. A.; Larrea, M. D.; Jasper, J. S.; McDonnell, D. P.; McCafferty, D. G. “Lysine-specific histone demethylase 1 inhibitors control breast cancer proliferation in ERα-dependent and independent manners.” ACS Chem. Biol. 2012, 7, 1221-1231.

Education
Ph.D., Duke University
Chemistry
Contact Information
C308 Gottwald Center for the Sciences
(804) 484-1578
(804) 287-1897 (Fax)
Areas of Expertise
Chemical Biology
Biochemistry
Organic Chemistry